Antimalarial Activity (Plasmodium falciparum 3D7) from Sea Sponge Acanthella sp.
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چکیده
منابع مشابه
Brine shrimp toxicity and invitro antimalarial activity of Citrus aurantifolia (Christm.) Swingle against Plasmodium falciparum 3D7
Malaria is one of the most prevalent, devastating parasitic infectious diseases in the world. In an attempt to search for new antimalarial compounds efforts are being made to do preliminary screening of aerial parts of the plant Citrus aurantifolia (Christm.) Swingle (family Rutaceae) at early flowering and fruiting stages against chloroquine sensitive Plasmodium falciparum 3D7 strain. The plan...
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BACKGROUND The objective of the current study was to assess the in vitro antiplasmodial activities of leaf, bark, flower, and the root of Pongamia pinnata against chloroquine-sensitive Plasmodium falciparum (3D7 strain), cytotoxicity against Brine shrimp larvae and THP-1 cell line. For in vivo study, the plant extract which has shown potent in vitro antimalarial activity was tested against Plas...
متن کاملFormamido-Diterpenes from the South China Sea Sponge Acanthella cavernosa
Seven new formamido-diterpenes, cavernenes A-D (1-4), kalihinenes E and F (5-6), and kalihipyran C (7), together with five known compounds (8-12), were isolated from the South China Sea sponge Acanthella cavernosa. Structures were established using IR, HRESIMS, 1D and 2D NMR, and single X-ray diffraction techniques. The isolated compounds were assessed for their cytotoxicity against a small pan...
متن کاملIn Vitro Cytostatic Effect of Extract from a Marine Streptomyces sp. on Plasmodium Falciparum 3D7
This study was designed to examine the stage dependency of growth inhibition by Streptomyces sp. crude extract and to determine whether its antimalarial activity is cytostatic or cytocidal. Growth inhibition was assessed by differences in growth appearance between treated and control parasites. Using synchronized In vitro cultures of Plasmodium falciparum strain 3D7, growth inhibition was detec...
متن کاملAntiplasmodial Activity of Isolated Polyphenols from Alectryon serratus Leaves Against 3D7 Plasmodium falciparum
Background Alectryon serratus was selected from a screening program devoted to search naturally occurring antimalarial compound from plants in Alas Purwo National Park, Banyuwangi, East Java, Indonesia. The previous studies showed that ethanol extract of A. serratus leaves contains some polyphenol compounds. Objective This study was designed to isolate and investigate antiplasmodial activity ...
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ژورنال
عنوان ژورنال: Natural-B
سال: 2012
ISSN: 2088-4613,2088-4613
DOI: 10.21776/ub.natural-b.2012.001.03.1